1994 kunde det bekräftas att mutationer i BRCA1-genen (breast cancer gene 1) de nu hittat ytterligare en markör, Lgr5, som gör att man kan hitta den tidigare.
LGR5 mouse monoclonal antibody, clone OTI2A2. View other "OTI2A2" antibodies (2) Get 29% off any Over-Expression Cell Lysate, a validated WB control, with any Ab purchase.
Location_base_pair. Starts at 71439798 and ends at 71586308 bp from pter ( according to hg38-Dec_2013) Fusion genes. (updated 2017) Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands) KIAA1033 (12q23.3) / LGR5 (12q21.1) 2020-06-10 LGR5 A gene on chromosome 12q22-q23 that encodes an orphan G protein-coupled receptor that is the stem cell marker of the intestinal epithelium and hair follicles. LGR5 is the target gene of Wnt signalling. Leucine-rich repeat-containing G-protein coupled receptor 5 ( LGR5) also known as G-protein coupled receptor 49 ( GPR49) or G-protein coupled receptor 67 ( GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins.
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If you continue, we'll assume that you are happy to receive all cookies. GeneCards ®: The Human Gene Database GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes. The knowledgebase automatically integrates gene-centric data from ~150 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site via CRISPR/Cas9 mediated recombination. Gene: LGR5; leucine rich repeat containing G protein-coupled receptor 5: Aliases: FEX, HG38, GPR49, GPR67, GRP49 : Location: 12q21.1: Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. PrimePCR™ PreAmp for SYBR® Green Assay: LGR5, Human Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. The gene LGR5 may have Genomic and Proteomic products available from Sigma-Aldrich.
2021-02-16.
HGNC data for LGR5. Approved symbol. LGR5. Approved name. leucine rich repeat containing G protein-coupled receptor 5. Locus type. gene with protein
Leucine-rich repeat-containing G-protein coupled receptor 5 ( LGR5) also known as G-protein coupled receptor 49 ( GPR49) or G-protein coupled receptor 67 ( GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins. LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene.
2007-10-14 · The Lgr5 (also known as Gpr49) gene is identified as a unique, single marker gene for adult stem cells and provides the first lineage tracing data for long-lived pluripotent stem cells in the
USD 170.00. Other products for "LGR5". cDNA Clones. Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5, also known as Gpr49) was selected from a panel of intestinal Wnt target genes for its restricted crypt expression.
Lgr5 tm2(DTR/EGFP)Fjs: Name: leucine rich repeat containing G protein coupled receptor 5; targeted mutation 2, Frederick J de Sauvage: MGI ID: MGI:5294798: Synonyms: Lgr5 DTR: Gene: Lgr5 Location: Chr10:115450314-115587780 bp, - strand Genetic Position: Chr10, 63.51 cM
Phenotype data for mouse gene Lgr5.
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A transcriptomics data-driven gene space accurately predicts img LGR5 promotes tumorigenicity and invasion of glioblastoma img. Misstänkta “Gene Expression Förändringar i skadade ryggmärgen efter transplantation av “LGR5 brist avreglerar Wnt signalering och leder till brådmogen panethceller Wnt Gene · HH Signaling · Canonical Wnt Pathway · Seven Transmembrane Porcupine Wnt · Wnt Signal · Wnt Stem Cell · Lgr5 Wnt · Frizzled Receptor 1994 kunde det bekräftas att mutationer i BRCA1-genen (breast cancer gene 1) de nu hittat ytterligare en markör, Lgr5, som gör att man kan hitta den tidigare. Wnt / ßcat och Met), WAP (för SV40Tag och Etv6 – Ntrk3) eller Lgr5 (för Pik3ca_mut).
Expression of Lgr5 protein in the human endometrium. Upper img. img 0. Addgene: HR180-LGR5-iCT img.
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FEX, GPR49, GPR67, HG38: Description. Leucine-rich repeat containing G protein-coupled receptor 5 (HGNC Symbol) Entrez gene summary.
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2020-07-01 · To identify new populations of LGR5 + cells that are prone to tumorigenesis, we utilized the tamoxifen-inducible Lgr5 cre/ERT2 allele in crosses with mice harboring Arid1a fl and (Gt)R26Pik3ca *H1047R alleles, a potent combination of cancer driver genes in the ovary and uterus (Chandler et al., 2015, Wilson et al., 2019).
LGR5 is used as a marker of adult tissue stem cells in the intestine, stomach, hair follicle, and mammary epithelium.1 Publication.
Manually curated information which has been inferred by a curator based on his/her scientific knowledge or on the scientific content of an article.